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Skin Boosters & Regeneration
Rejuran Healer in Seoul: Polynucleotide Skin Booster
Quick answer
Rejuran Healer is a Korean skin booster made of polynucleotides (PN) derived from salmon DNA, injected into the skin to support repair, improve texture and elasticity, and help the skin look healthier over time. At The Heal in Jamsil, Seoul, a dermatologist usually plans a course of about three sessions a few weeks apart. Small bumps settle within a day or so. Send your skin concerns and dates for a tailored plan.
Medically reviewed by Dr. Yang Jeong-hwa , board-certified dermatologist · Updated October 2026
Procedure time
30–40 min
Downtime
1–2 days bumps
Results visible
2–4 weeks
Sessions
Usually 3
What is Rejuran Healer?
Rejuran Healer is a polynucleotide (PN) injectable developed in Korea. Polynucleotides are chains of DNA fragments, purified from salmon, that are thought to support the skin's natural repair processes and the activity of fibroblasts, the cells that produce collagen. Unlike fillers, Rejuran is not designed to add volume. Instead, it is placed in many small deposits across the skin to improve overall quality: finer texture, better elasticity and a calmer, healthier look. It has become one of the most popular skin boosters in Korea and is increasingly requested by international visitors.
What can it help with?
- Rough or uneven texture and early fine lines; see uneven skin texture .
- Thin, fragile or sensitive skin that needs support; see thin skin .
- Recovery after lasers or other procedures, as part of a plan.
- Enlarged-looking pores and dullness.
- Shallow acne scars , often in combination with other treatments.
Results are gradual and vary with age, skin type and lifestyle. Rejuran is often chosen as a gentle step toward healthier skin rather than a dramatic change. Dr. Yang will tell you which concerns are likely to respond and which need another approach.
Who is a good candidate?
Rejuran suits adults who want stronger, smoother and more resilient skin, including those with sensitive skin who may not tolerate aggressive treatments. It is also popular before events because the effect looks natural. We do not recommend it during pregnancy or breastfeeding, over active infection or acne flares at the injection sites, or for people with allergies to fish or salmon-derived products. Please let us know about blood-thinning medication, which can increase bruising. If your main concern is sagging or deep wrinkles, lifting or other approaches may be more effective, and Dr. Yang will say so.
Treatment day and the course of sessions
After cleansing, numbing cream is applied for about 30 to 40 minutes, because PN injections are known to be more noticeable than some boosters. Small amounts are then injected across the face by hand or with an injector device. Afterward you will see small raised bumps at the injection points, which usually flatten within a day, and occasionally pinpoint bruises. Makeup can usually be applied the next day. A typical course is about three sessions, spaced two to four weeks apart, with maintenance every few months. See how many skin booster sessions you need .
Planning Rejuran around your trip
If you can stay in Seoul for a few weeks, the full course can be completed here. Visitors on shorter trips often have one session now and continue on later visits, or combine Rejuran with another treatment to make the most of one appointment. The small bumps are the main visible downtime, so we suggest a free evening after treatment rather than an important dinner or photoshoot. To compare Rejuran with other boosters, read Rejuran vs Juvelook , or ask us for a booster plan based on your skin and travel dates.
The Heal approach
We use Rejuran to rebuild skin quality first, then add lifting or brightening only where it is still needed.
Expert review
Dr. Yang Jeong-hwa
Medical Director · Board-certified dermatologist · Seoul National University College of Medicine
Written for international patients and reviewed for medical accuracy. Individual results vary; your plan is decided in person after a skin assessment. Our review policy
Visit us
The Heal Dermatology Clinic Jamsil
4F, 329 Olympic-ro, Songpa-gu, Seoul, Korea
5 min walk from Jamsil Station (Line 8), Exit 9
Mon & Fri 10:00–20:00
Tue–Thu 10:00–19:30
Sat 09:30–16:00 · Sun & holidays closed
International patients
Visiting Seoul? Get your plan before you fly.
English consultations with a board-certified dermatologist, 5 minutes from Jamsil Station. Treatments are scheduled around your downtime and flights. International patient guide
1
Message us
Concerns, optional photos and travel dates via form or KakaoTalk.
2
Get your plan
Suggested treatments and timing around your flights.
3
Consult & treat
In-person assessment with Dr. Yang in English, then treatment.
Frequently asked
Rejuran Healer: your questions answered
Does Rejuran hurt?
PN injections can feel sharper than some other boosters, so we apply numbing cream for 30 to 40 minutes beforehand. Most patients find it tolerable, and the discomfort stops when the injections finish.
When will I see results from Rejuran?
Many people notice smoother, more hydrated-looking skin within two to four weeks of the first session. Improvements build with each session in the course, and results vary between individuals.
How long does Rejuran last?
After a completed course, results commonly last several months. Many patients choose a maintenance session every three to six months, depending on their skin and goals. Results vary between individuals.
Can I combine Rejuran with lasers or lifting?
Yes. Rejuran is often combined with energy treatments or lasers to support skin quality. Dr. Yang will advise on the order and spacing so that each treatment works well. Many patients combine them in one visit.
Keep exploring
Related treatments & guides
English consultations in Jamsil, Seoul
Rebuild stronger, smoother skin with Rejuran
Send your photos and travel dates. We reply with a personalised plan before you fly.